Development of functional genomics screens for osteoarthritis associated genes in MSC-derived osteoblasts and chondrocytes

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Delineation of insulin signalling

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Dissecting insulin signals with a view to generate safer therapeutics

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Development of an osteoarthritis drug screening tool using engineered stem cell lines to identify novel mechanisms of disease biology

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Improving the Efficiency of Exosome Biogenesis within Mesenchymal Stem Cells

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Development of an experimentally tractable in vitro human model of osteogenesis

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A biotherapeutic loading platform using extracellular vesicles derived from immortalised mesenchymal stem cell lines.

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